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Recombinant Human IL

Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes PBL Yokota T et al 1986 Proc Natl Acad Sci USA 83 5894 The ED 50 for this effect is 0 1-0 5 ng/mL The specific activity of Recombinant Human IL-7 is...

Emerging therapeutic agents for genitourinary cancers

nbsp 0183 32 The treatment of genitourinary malignancies has dramatically evolved over recent years Renal cell carcinoma urothelial carcinoma of the bladder and prostate adenocarcinoma are the most commonly encountered genitourinary malignancies and represent a heterogeneous population of cancers in both histology and approach to treatment However all three cancers have undergone paradigm shifts in...

Accelerated immunosenescence in rheumatoid arthritis

nbsp 0183 32 Patients with rheumatoid arthritis RA develop features of accelerated ageing including immunosenescence These changes include decreased thymic functionality expansion of late-differentiated effector T cells increased telomeric attrition and excessive production of cytokines senescence-associated secretory phenotype The progression of RA has been associated with the...

Recombinant Human Wnt

Authors Cohen E Miller M Wang Z Moon R Morrisey E Development 2012 139 11 1931-40 Species Mouse Sample Types Whole Cells Applications Bioassay Derivation of...

PDF Transduction as a Potential Dissemination

nbsp 0183 32 The qnrB19 gene had already been reported in food-producing animals such as pigs poultry and veal calves sometimes associated with mobile genetic...

Mendelian randomisation study of the effects of known

nbsp 0183 32 Methods We conducted a two-sample Mendelian randomisation MR study using publicly available data for genetic variants associated with the factors of interest and summary genetic data from genome-wide association studies of the Pancreatic Cancer Cohort Consortium PanScan and the Pancreatic Cancer Case-Control Consortium PanC4 including in total 8769 cases and 7055 controls...

Immediate and long

nbsp 0183 32 A substantial number of clinical studies have demonstrated the functional recovery induced by the use of brain-computer interface BCI technology in patients after stroke The objective of this review is to evaluate the effect sizes of clinical studies investigating the use of BCIs in restoring upper extremity function after stroke and the potentiating effect of transcranial direct current...

Emotional Lability at Disease Onset Is an Independent

nbsp 0183 32 Miller A Pratt H Schiffer RB 2011 Pseudobulbar affect the spectrum of clinical presentations etiologies and treatments Expert Rev Neurother 11 7 1077-88 18 Smith RA Berg J Pope L Thisted R 2003 Distinguishing affective disorders in amyotrophic...

Methylome profiling of young adults with depression

nbsp 0183 32 Currently the leading cause of global disability clinical depression is a heterogeneous condition characterised by low mood anhedonia and cognitive impairments Its growing incidence among young people often co-occurring with self-harm is of particular concern We recently reported very high rates of depression among first year university students in Northern Ireland with over 25 meeting...

Neurobehavioral dysfunction in non

nbsp 0183 32 Non-alcoholic steatohepatitis NASH is one of the most prevalent diseases worldwide While it has been suggested to cause nervous impairment its neurophysiological basis remains unknown Therefore the aim of this study is to unravel the effects of NASH through the interrelationship of liver gut microbiota and nervous system on the brain and human behavior To this end 40 Sprague-Dawley...

Matrix metalloproteinase9 as the protein target in anti

nbsp 0183 32 The discovery and development of anticancer still remain a challenge especially regarding the problem of cancer cell selectivity Matrix metalloproteinase MMP was broadly studied as one of the protein targets to stop cancer angiogenesis as well as its cell migration The MMP degrades extracellular matrix ECM such as collagen and gelatin which are important to control the cell migration...

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